2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100635R
    Diacetolol (Standard)
    Oleic acid (Standard) is the analytical standard of Oleic acid. This product is intended for research and analytical applications. Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activator.
    Diacetolol (Standard)
  • HY-Y1117S2
    Melamine-15N3,13C3
    Melamine-15N3,13C3 is a 13C- and 15N-labeled Melamine (HY-Y1117). Melamine is a metabolite of cyromazine. Melamine is a intermediate for the synthesis of melamine resin and plastic materials.
    Melamine-<sup>15</sup>N<sub>3</sub>,<sup>13</sup>C<sub>3</sub>
  • HY-B0794A
    AZ7550 hydrochloride
    		98.66%
    AZ7550 hydrochloride is an active metabolite of AZD9291 and inhibits the activity of IGF1R with an IC50 of 1.6 μM.
    AZ7550 hydrochloride
  • HY-101403A
    Monoacetylcadaverine hydrochloride
    		98.0%
    Monoacetylcadaverine hydrochloride is a metabolite of the endogenous polyamine cadaverine.
    Monoacetylcadaverine hydrochloride
  • HY-N10322
    2-Hydroxyemodin
    		99.74%
    2-Hydroxyemodin is an active metabolite of emodin in the hepatic microsomes. Emodin is an anthraquinone present in fungal metabolites and constituent of rhubarb. 2-Hydroxyemodin proves to be mutagenic to Salmonella typhimurium TA1537 in the absence of activation system.
    2-Hydroxyemodin
  • HY-125446
    2-Hydroxymethyl olanzapine
    		98.45%
    2-Hydroxymethyl olanzapine is a metabolite and a degradation product of Olanzapine (HY-14541)[1][2].
    2-Hydroxymethyl olanzapine
  • HY-148225
    Fulvestrant 3-β-D-Glucuronide
    Fulvestrant 3-β-D-Glucuronide, a metabolite, is glucuronide and sulfate conjugates of Fulvestrant (HY-13636), a pure anti-estrogenic steroid. Fulvestrant 3-β-D-Glucuronide can be used for the research of breast cancer.
    Fulvestrant 3-β-D-Glucuronide
  • HY-136612
    DCBA
    		99.65%
    DCBA is a metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). The concentration of DCBA in urine can assess exposure to DEET.
    DCBA
  • HY-135325
    4-Hydroxyacetophenone oxime
    		99.96%
    4-Hydroxyacetophenone oxime is an impurity of Acetaminophen (Paracetamol). Acetaminophen is a potent cyclooxygenase-2 (COX-2) and hepatic N-acetyltransferase 2 (NAT2) inhibitor, and used antipyretic and analgesic agent.
    4-Hydroxyacetophenone oxime
  • HY-W016099
    3-Methyl-2-quinoxalinecarboxylic acid
    3-Methyl-2-quinoxalinecarboxylic acid (MQCA), an important N-oxide reductive metabolite of Quinocetone or Olaquindox, potently inhibits the growth of Chang liver cells through S phase arrest of the cell cycle.
    3-Methyl-2-quinoxalinecarboxylic acid
  • HY-116617
    15-Keto Travoprost
    		99.20%
    15-Keto Travoprost (15-Keto Fluprostenol isopropyl ester) is a metabolite of Travoprost (HY-B0584). 15-Keto Travoprost shows stimulatory effect on the growth and thickening of the eyelashes.
    15-Keto Travoprost
  • HY-78841
    (2S,4S)-Sacubitril
    (2S,4S)-Sacubitril is the impurity of Sacubitril. Sacubitril is a potent NEP inhibitor that can be used for the research of heart failure.
    (2S,4S)-Sacubitril
  • HY-N0384S1
    Homovanillic acid-d2
    		99.51%
    Homovanillic acid-d2 (Vanilacetic acid-d2) is the deuterium labeled Homovanillic acid (HY-N0384). Homovanillic acid (Vanilacetic acid) is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
    Homovanillic acid-d<sub>2</sub>
  • HY-125780
    5-Phenylhydantoin
    5-Phenylhydantoin is an antiepileptic compound, and has certain hypolipidemic compound.
    5-Phenylhydantoin
  • HY-18719ES
    Endoxifen-d5
    Endoxifen-d5 is the deuterium labeled Endoxifen. Endoxifen is a key active metabolite of tamoxifen (TAM) with higher affinity and specificity to estrogen receptor that also inhibits aromatase activity. Endoxifen has the potential for breast cancer study.
    Endoxifen-d<sub>5</sub>
  • HY-129043
    3-Formyl rifamycin
    		98.50%
    3-Formyl rifamycin is an acid degradation product of the broad-spectrum antibiotic Rifampicin (HY-B0272). 3-Formyl rifamycin forms via acid hydrolysis of Rifampicin in an acidic environment.
    3-Formyl rifamycin
  • HY-118093
    N-benzoyl-L-aspartic acid
    		99.89%
    N-benzoyl-L-aspartic acid, a major metabolite of benzyl glucosinolate, can be used for modification of peptides or proteins.
    N-benzoyl-L-aspartic acid
  • HY-136428
    Desoxycarbadox
    Desoxycarbadox is a metabolite of Carbadox (HY-B1340). Carbadox is a quinoxaline-di-N-oxide antibiotic compound.
    Desoxycarbadox
  • HY-118167
    Monoethylglycinexylidide
    		99.69%
    Monoethylglycinexylidide is a metabolite of Lidocain (HY-B0185) via oxidative N-deethylation of Lignocaine by liver cytochrome P-450 enzymes in the liver[1].
    Monoethylglycinexylidide
  • HY-B2150
    4-Hydroxyantipyrine
    		99.9%
    4-Hydroxyantipyrine (4-Hydroxyphenazone; NSC 174055) is the major metabolite of Antipyrine (HY-B0171), can be as a biodistribution promoter. 4-Hydroxyantipyrine can increase distribution of concentration ratio of Citicoline and Antipyrine in the brain.
    4-Hydroxyantipyrine
Cat. No. Product Name / Synonyms Application Reactivity